The Nevada Division of Public and Behavioral Health contracted with the University of Nevada, Reno, School of Public Health to conduct the YRBS in all middle schools throughout the state. The 2023 Nevada Middle School YRBS provides statewide data to assess priority health-risk behaviors among middle school students; measure progress toward achieving national health objectives for Healthy People 2030 and other program and policy indicators; and evaluate the impact of school and community interventions at the national, state, and local level. It is our intention that these data will be used by education and health professionals, policy makers, community members, and researchers to improve the health of Nevada’s middle school students.