Home visiting programs address a broad range of outcomes related to maternal, family, and child well-being, impacts were estimated on 66 outcomes. This report examines the effectiveness of home visiting across groups of outcomes organized into eight pre-specified topical research questions, using omnibus tests to look beyond effects on individual outcomes. MIHOPE found statistically significant and positive effects of home visiting for the five research questions that measured maternal and family well-being outcomes. MIHOPE found some evidence of positive effects of home visiting for the three research questions related to child functioning outcomes.